PURE ENCAPSULATIONS - MethylAssist - 90 Vegetable Capsule(s) - NPN: 80047036 -- MethylAssist provides activated B vitamins, including Metafolin® L-5- methyltetrahydrofolate (L-5-MTHF), to support nutrient metabolism. Activated B vitamins are particularly important for providing methyl groups involved in the methylation cycle. Methylation involves the transfer of a methyl group (CH3) from one molecule to another. Vitamin B12 and folate are required by the enzyme that produces methionine. Folate is provided in this formula as Metafolin®, the naturally occurring, universally metabolized form of folate. Metafolin® is chemically identical to the active folate metabolite, 5-methyltetrahydrofolate (L-5-MTHF). L-5-MTHF is the predominant, naturally occurring form of folate in food. Through bypassing several enzymatic activation steps, it is directly usable by the body and provides all of the benefits of folic acid regardless of functional or genetic variations. In addition, these B vitamins also help to form red blood cells. MethylAssist also includes benfotiamine, a synthetic derivative of thiamine reported to have better bioavailability than thiamine itself.Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.BenfoPure® is a registered trademark of Hamari Chemicals USA, Inc.